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The Class 3 indicator specifically reacts to a single critical sterilization parameter, which is typically temperature. This type of indicator is designed to provide a pass/fail result for a specific sterilization process, confirming that the necessary temperature has been achieved for effective sterilization. Class 3 indicators are often used to monitor steam sterilization cycles, where reaching the correct temperature is critical to ensure that the sterilization process is effective in killing microorganisms.

In contrast, other indicators react to multiple parameters or different aspects of the sterilization process. For instance, some Class 5 indicators monitor a combination of conditions, including time and temperature, which would not apply to a Class 3 indicator. Similarly, options related to exposure to radiation or air removal efficacy do not pertain exclusively to temperature and thus are not characteristic of a Class 3 indicator's function. Overall, the key characteristic of the Class 3 indicator is its focus on a single critical sterilization parameter, making its role essential in ensuring the sterility of healthcare materials.